I wanted to clarify that the theme you select is tied to your user. While the site admin can set a default theme, you can go into your user settings and set whatever theme you prefer which overrides the default theme. Also, I don’t advocate the site should default to any one series specific theme, but stick with a generic one.
So one could set LCARS as their theme, or Picard, or SNW, or Discovery, and it would have no bearing on how others see the site. Of course someone needs to create all those themes, and the site admin needs to install them to make them available to everyone.
This does bring up a valid point about accessibility. Someone should definitely create some themes focused on accessibility.
Someone with better CSS/UI skills than me will do it, and it will be fabulous! Just wait and see.