@Kyoyeou@slrpnk.net seems to have given all the background info :)

Sure.

The problem is that the brain is not a squishy uniform cell mess that just reacts to some chemicals (dopamine/serotonine/…). All of those are neurotransmitters to specific classes of neurons that have a very specific topological position to perform their function.

So if you just throwing in random neurons here and there, they won’t do anything. They are not contributing to any pathways.

Serotonin re-uptake inhibitors and dopamine generator drugs (aka opioids) make the signal send by the “correct” neurons that are there stronger, contributing to the desired effect.

The problem with Alzheimers is the death of “correct” neurons, that occurs before Alzheimer is manifested. So just injecting new ones is unlikely to do anything.

Moreover, the neurons don’t just live outside brain. They need to be immortalized to live in a Petri dish. And to acheive it, the only way we can go now is to add factors that in the context of human organism are considered as cancerous.

So it’s a combo of “unlikely to be efficient” and “potentially likely to lead to cancer”. With Parkinson the tradeoff might be acceptable, but this kind of projects is definitely that raises some red flags for me.

A) We already don’t know how neurons interconnect (eg why infants loose ~ 70% of their neuron connections between 1 and 3 years). B) That’s not how dopanime works C) That’s not how Parkinson works either

I find it fascinating how few people remember the time when Greenpeace was literally selling Russian gas.

No, no - it’s just as scientists predicted. In the worst-case “no-mitigation” scenario and with attempts from them to explain that +2 global will likely be +10 in peak temperature increase over land (read US, Europe, Asia). As in, both mean and std will increase, but without ocean’s mitigation over land.

Fucked is not the correct word - there is a +50 predicted before the end of decade in Strasbourg, where I am from. There is not a single building built there made to resist that kind of temperatures, nor a single tree or crop that could stand that for a day.

And it’s a relatively “safe” area as far as long-term projections go…

Yes, although most of the time they are not provided, so I make my own out of TP. If not, I have a desinfectant spray on me that can clean the sit if it is not too disgusting.

Yes - generally beans are both healthy (33% protein, 33% fiber, 33% carbs), cheap (dried or in cans), and can be pretty tasty, even out of cans, but if not with eggs, as part of a soup (tomatoes + grain + spices + veggies).

Generally, I don’t like to gloat, but I did call that one ~ June 5th over on Reddit (https://www.reddit.com/r/france/comments/140qkwu/destructions_incursions_évacuations_dans_la/jmyndp3/?context=3; in French because it was on r/France).

It actually is much worse than it seems - I did a write up over on Mastodon to explain why and how (https://mastodon.social/@andrei_chiffa/110599724720727202). The TLDR is that cities taken by Wagner mercs will be hard to retake without leveling, all internal protection troops are either tied or were lost in Ukraine, and mercs themselves have nothing to loose and all the revenge to take.

It’s fediverse. You don’t like an instance, you create your own and defederate from the ones you don’t like. That’s the nice thing about it.

People that have ~1 week of ping time (as yours truly) are finally getting to their todo list item of checking alternatives to Reddit and making an account and first posts :)

Du coup, vu que c’est plus airfrance, est ce qu’on peut se designer comme france-surmulot-monde?