• Bleeping Lobster@lemmy.world
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    11 months ago

    I lost a friend to ket. He was partying with bad people, he was sick, choked on his vomit and they stole his stuff / left him to die.

    Ketamine is a very interesting ride, and has wonderful potential as an antidepressant, but for the love of yourself (and my badly missed friend, John the magic man), PLEASE have someone compus mentus watching over you while you experience it, if you choose to do so.

    Also strongly recommend you DO NOT mix with alcohol.

    • jeffw@lemmy.worldM
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      11 months ago

      And always review information on erowid’s website before using any drug

    • flooppoolf@lemmy.world
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      11 months ago

      Ketamine also should not be used in people with high blood pressure as it may further increase it and heart rates to dangerous levels.

      Hot tubs increase heart rate as well however the blood pressure is lowered.

      Oh yah, he had heart disease which is a no go with hot tubs.

    • kboy101222@lemm.ee
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      11 months ago

      They gave me ketamine the last time I was in the hospital for pain so they could knock me out.

      It was the single worst experience of my life, even worse than the injury I was being knocked out for. I was semi conscious the entire time, but I couldn’t feel or hear anything. I just knew people were all around me doing something. It feels like I was dead for a while. I have very few memories from the time they first gave it to me in the ambulance to the time I woke up at home the next day.

      Fucking awful experience all around. Next time I was in the hospital for an unrelated condition I told them I’d rather have zero pain medicine than even a tiny amount of ketamine

        • kboy101222@lemm.ee
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          11 months ago

          They gave me low dose in the ambulance. While it was a decent high, I still had the same memory issues (which I always have while high, but at least I can normally remember something)

            • kboy101222@lemm.ee
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              11 months ago

              Good to know, especially since the ambulance really didn’t give me much.

              I’m still gonna pass on it though cause that was such an awful experience and I’d much rather just take an edible

      • wia@lemmy.ca
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        11 months ago

        I don’t understand why this is bad?

        I’m reading this like you’re unhappy you don’t remember the pain? And you want pain?

        Or is this sarcasm?

        • kboy101222@lemm.ee
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          11 months ago

          No, it’s basically an entire day of my life that I know happened but I can’t remember any specific details of. I know I went through insane amounts of physical and emotional trauma (I laid there in pain for no less than 8 hours because it was literally the same week COVID started), and not being able to remember it at all is preventing me from moving on or healing.

          Idk if it’s just a me thing, but I hate not remembering entire large sections of time. After the first time I got black out drunk I didn’t drink alcohol for almost 2 years

      • chitak166@lemmy.world
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        11 months ago

        Do you know why they gave you ketamine instead of something more standard like morphine?

        • kboy101222@lemm.ee
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          11 months ago

          Absolutely no idea. The other hospital I mentioned was confused as to why they did it as well.

    • chitak166@lemmy.world
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      11 months ago

      Doesn’t surprise me at all!

      The groups of ‘friends’ that do shit like ketamine are almost always scumbags just keeping each other down.

      • Bleeping Lobster@lemmy.world
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        11 months ago

        I think you and I had very different experiences! While ket abuse can defo lead to paranoia and becoming more insular, in my circles it was taken at hard house / trance events or after parties. Lots of silliness and fun times.

        Unfortunately for my friend, he lived on his own in Manchester and fell in with a rough crowd after moving to Salford :'(

  • HonoraryMancunian@lemmy.world
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    11 months ago

    Matt Le Blanc:

    "…I guess you’re keeping the 20 bucks you owe me.”

    This is exactly the kind of humour Perry would’ve appreciated

  • fosforus@sopuli.xyz
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    11 months ago

    And Elon Musk eats that stuff for breakfast and keeps truckin’ on. Life is unfair.

    • NoSpiritAnimal@lemmy.world
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      11 months ago

      He is not just truckin’ along. The man looks like someone’s aunt is trying to build mass. He looks like an uncooked weisswurst got a planet fitness membership. He is a torso made manifest. Hair plugs and ozempic riding the right-wing-pipeline down a k-hole.

    • sharpiemarker@feddit.de
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      11 months ago

      Hot tubs + drugs don’t mix. Even alcohol is dangerous because the effect of the hot tub increases the effects. We bought a hot tub recently and they’re are dozens of warnings about drugs/alcohol.

      My recommendation to Elon would be to have a nice big dose and take a long dip.

  • spiderkle@lemmy.ca
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    11 months ago

    Takes note: Don’t do horse-tranquilizers alone in a bath, check. As a matter of fact don’t do any analgesic/anesthetic with additional drugs in a bath, also check.

    • RocketBoots@programming.dev
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      11 months ago

      Calling them horse tranquilizers is misleading. Ketamine was and still is used in medicine and is on the WHO list of essential medicines.

      My cat is prescribed gabapentin. Some even get tramadol. Warfarin literally was rat poison until we got all but the craziest SOBs with an abundance of vitamin K in they’re veins.

      • Dozzi92@lemmy.world
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        11 months ago

        Yeah, I feel like there is a war on K because it can absolutely replace opiates in pre-hospital pain management. Break a leg? Let the medics hit you with ketamine. Oh, your BP is a little low? No worries, ketamine doesn’t care.

        It is better than an opiate with none of the contraindications. And I’m oversimplifying, but I can’t help but think some of this news coming out is almost a hit piece to dub ketamine dangerous, when it is, in fact, magnitudes safer than opiates.

      • Hadriscus@lemm.ee
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        11 months ago

        oh, I tried that last month ! Pretty sweet high, relaxing. Like a really soft mdma (really soft!)

        (I was talking about gabapentin, just realized it was ambiguous)

  • Rob T Firefly@lemmy.world
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    11 months ago

    When Friends was current I wasn’t a fan, the small bits I’d seen mostly annoyed me and - disaffected gothy teens/early twenties guy that I was - I dismissed it as one of those things everyone in the mainstream liked and was therefore obviously garbage.

    Nowadays I’m married to a Friends fan who has begun showing me the series. As we progress through the box set I’m realizing it’s actually pretty good, a couple of the characters actually still annoy me when they’re focused on but there’s a ton else going on that’s pretty entertaining. I’m particularly surprised to be enjoying Chandler so much.

    It’s very sad what Matthew Perry went through in life and how he died, but I’m now belatedly appreciating some of the work he did.

      • kameecoding@lemmy.world
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        11 months ago

        you can’t just do that mate, same with Seinfeld, they were filmed in front of a live audience, they had to stop for laughter otherwise you wouldn’t hear what they are saying.

        or are you gonna come out and say Seinfeld isn’t hilarious?

    • Underwaterbob@lemm.ee
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      11 months ago

      I’m still not sure I’d call it good, but it was a big step up from sitcoms before it. It tried pretty hard to not be sexist, and introduced some diversity that wasn’t just John Ritter pretending to be gay for lulz. It is still spectacularly unrealistic, but whatever. It’s a sitcom! It does have some genuinely funny moments.

      I still periodically get “Smelly Cat” stuck in my head. Fuck, I’m guilty of making Ross-esque synthesizer music…

      • Rob T Firefly@lemmy.world
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        11 months ago

        Very true. There are also definitely still some 1990s-era LGBTQIA+ phobic jokes which were wrong then and really stick out now, but in general I’d call the writing surprisingly decent.

        As a New Yorker, though, I still couldn’t afford that apartment in a million years.

        • Tavarin@lemmy.ca
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          11 months ago

          I still couldn’t afford that apartment in a million years.

          Neither could they, it was rent controlled due to Monica’s grandmother living there, and they illegally kept her name on the lease for the cheap rent.

          And Chandler made good money, so he could afford the smaller 2 bedroom.

  • saze@feddit.uk
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    11 months ago

    Damn, I did not know Ket could depress respiration like this! In fact Ket is used medicinally in place of opioids as it doesn’t depress respiration. But here is the TIL part: it should not be mixed with benzos or alcohol (or other depressants I would imagine). I don’t use bu I hope someone who does get to read this.

    • 14th_cylon@lemm.ee
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      11 months ago

      ketamine is anaesthetic and was used in the past in combat medicine and such, because it is quite safe when administered by untrained staff. the fact it is used to treat depression is new to me, but getting in the pool while high on it is the most stupid idea ever :(.

    • prole@sh.itjust.works
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      11 months ago

      He was in the bathtub and drowned. If you take enough ketamine, it will literally incapacitate you (for many, that’s the entire point). He did this in a bathtub.

      He did not die from overdosing on ketamine, because that’s nearly impossible. He was stupid and incapacitated himself in a bathtub and drowned. It sucks, and it’s easy to just blame a chemical.

      I’m sure there are people who die after having a couple drinks and getting into the tub, but do we then say that they “died due to the acute effects of alcohol”? No. We say they drowned.

  • IDontHavePantsOn@lemm.ee
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    11 months ago

    Im fairly certain that what I’m about to say will be disliked by ketamine users and abstainers.

    Ketamine is garbage at everything besides temporarily lobotomizing people. It works for it’s many uses because it makes the user stupid. It’s often given to suicidal people, not because it’s a miracle drug, but because it incapacitates them in a safe manner.

    That said, it’s great at making people too stupid to be able to hurt themselves, most of the time. It’s great at numbing psychological pain because the user will be too stupid to conceptualize their own thoughts or realize where they are physically.

    It’s also hard on the urinary system and has a fleeting high.

    If you like ketamine then by all means, you do you. If you may be interested in trying ketamine, become a zombie safely, just don’t expect it to cure your depression, woes, or any of your other problems.

    • StorminNorman@lemmy.world
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      11 months ago

      Yeah, I’m gonna take the peer reviewed studies results that show that ketamine is quite effective with relieving drug resistant depression over this post of yours…

      • figaro@lemdro.id
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        11 months ago

        It is useful in creating a sense of disassociation of self - the same thing that meditation does. It even affects the same regions of the brain as meditation. When used carefully, with therapeutic intent, it can be an effective treatment for depression.

        Recreational use is sketchy, definitely. But the science is there for using it therapeutically.

      • dangblingus@lemmy.dbzer0.com
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        11 months ago

        But your assessment of its efficacy is not contradictory to DontHavePants observation. They didn’t say it wasn’t effective.

      • madcaesar@lemmy.world
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        11 months ago

        I have no dog in this fight, but any studies done on brain chemistry and psychological effects need to be taken with a grain of salt. We know so little about the brain and consciousness that most of the stuff we’re trying and doing are educated guesses.

        • StorminNorman@lemmy.world
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          11 months ago

          Ketamine is garbage at everything besides temporarily lobotomizing people. It works for it’s many uses because it makes the user stupid. It’s often given to suicidal people, not because it’s a miracle drug, but because it incapacitates them in a safe manner.

          This quote from you contradicts what you’ve just said.

          • IDontHavePantsOn@lemm.ee
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            11 months ago

            It doesn’t. I can speak to it’s mode of action without speaking to it’s reason of use or efficacy. It’s highly effective. It’s great at what it’s used for. It also temporarily makes the user stupid and incapacitates them.

            • Metacortechs@lemmy.world
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              11 months ago

              That isn’t it’s mode of action, at all.

              It also doesn’t make you stupid, it is a disassociative anesthetic so you lose touch, to varying degrees, of your senses. At high enough doses even your sense of hearing becomes strange and I would bet if my doc gave me more it would fail almost completely. That’s not a place I want to go however.

              Despite that, and appearing to be incapable of coordinated movement or speech, the mind is still active. Altered, yes. But active and intact. I am always aware of my partner in the room/bed with me, the dog checking things out, I just choose not to interact with them to continue exploring memories, or alien landscapes, or just turn off my mind, listen to the music, and let the drug work while the most fantastic and surreal images come and go.

              I’m here today because of ketamine. Disinformation and pearl clutching threatens to reduce access to it, and could cost lives, speaking only of this one niche use.

              • IDontHavePantsOn@lemm.ee
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                11 months ago

                I’m not trying to diminish anyone’s experiences with ketamine, or reduce anyone’s access to it, though I do think it’s funny everyone thinks that some asshole on the internet has that ability.

                Are you able to stand up when using ketamine? How about run? Could you tell me your personal details such as name/date/address? Could you tell me the time? Could you remember your mother’s phone number? Could you take a bath? Could you safely use a knife? Could you melt into nothingness and lose all sense of self, physicality and emotion?..wait strike that last one. Of course you could.

                Now we’re at the point that we all realize dissociation is to become stupid and incapacitated. Anesthitized even?

                • StorminNorman@lemmy.world
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                  11 months ago

                  Ahhhhh, so you did come back to say more dumb stuff. I literally baby sat a group of friends on the stuff two weekends ago. Sure, they said some amusing things, but at least 95% of what they said was perfectly coherent and made sense. As evidenced by one of them saying “you know you’re getting old when you have more cos you’re lower back starts to ache”. By your description, that should not have been possible. Yet it was. Sure, you enter a k-hole and you’re good for nothing, but most K experiences don’t enter that and people can function fine enough on it - like most drugs the intensity of effect is dose dependent. But like I said in a previous comment, you seem to be stuck in the 1950s and their anti drugs hysteria.

              • IDontHavePantsOn@lemm.ee
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                11 months ago

                I’ve ingested a ton of ketamine myself, so theres no pearl clutching here. I’ll be back tomorrow to continue arguing semantics.

                • prole@sh.itjust.works
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                  11 months ago

                  So you sound like someone with some experience using drugs (particularly those of psychedelic or hallucinatory nature), right?

                  So you would know that drugs effect everyone differently. Personally, I never abused ketamine, but I have k-holed a handful of times, and my personal experience was that it had a profound effect on me in many ways.

                  But that’s just my personal experience. Nothing more, nothing less.

                  Anyway, those who know, know MXE (methoxetamine) was way better for that brief period of time before the supply permanently dried up.

            • StorminNorman@lemmy.world
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              11 months ago

              You didn’t though. You used a blanket statement. As evidenced by your use of the word “everything”. Your entire initial comment reads as if it was written in the grip of anti drugs hysteria in the 1950s and shows none of the nuance you’re now trying to claim it does.

              You’re also wrong on its mode of action, so you’re not even speaking to that. It doesn’t work by making the user “too stupid to conceptualize their own thoughts or realize where they are physically”.

              • chitak166@lemmy.world
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                11 months ago

                He said everything except “temporarily lobotomizing people” which was clearly hyperbole.

                He then gave examples where the sedation provided by ketamine can be beneficial.

    • prole@sh.itjust.works
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      11 months ago

      Or, get this, everyone experiences drugs differently and your bad anecdote is irrelevant next to the mountains of evidence and peer reviewed studies.

      • IDontHavePantsOn@lemm.ee
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        11 months ago

        Once again, I haven’t disputed or attempted to refute any of these “mountains of evidence.”

    • butterflyattack@lemmy.world
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      11 months ago

      I would add to this that anyone doing ketamine should not do it in the bath, which seems to be what happened here. The same happened to someone I knew, she drowned in the tub.

      • driving_crooner@lemmy.eco.br
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        11 months ago

        Any drug close water where you can drown is a recipe for disaster. Someone I knew pop and acid tab at the beach and drown itself.

      • prole@sh.itjust.works
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        11 months ago

        Yeah, “don’t k-hole in the bathtub” seems like pretty good (and hopefully obvious) advice. This seems more like user error than the acute effects of the drug itself.

        He didn’t die from overdosing on ketamine, because that’s nearly impossible.

        He drowned.

    • ImFresh3x@sh.itjust.works
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      11 months ago

      I judge my desire to try drugs by how people act when they’re on them. Do they look like they’re having fun at least? Two drugs I’ve never had an interest in:

      Ketamine

      Nitrous

      • prole@sh.itjust.works
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        11 months ago

        That’s unfortunate. The effects of many drugs can be entirely mental rather than visual, leaving the person looking like they’re just laying down with their eyes closed, or staring into space.

        Particularly, ketamine, as a dissociative, at higher doses, is entirely in your mind. What a person in that state looks like from the outside is zero indication of what they are experiencing.

        • ImFresh3x@sh.itjust.works
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          11 months ago

          It’s not unfortunate. To me drugs are entirely unnecessary to begin with. And if I choose to use them it’s to enhance an activity, not to replace an activity or be an activity on its own. I’ll be fine.

          • prole@sh.itjust.works
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            11 months ago

            Well that’s not what we were talking about though, was it? We were talking about you judging people based on how they may look while under the influence. That’s ignorant.

            Also, I find this to be amusing:

            To me drugs are entirely unnecessary

            Uh huh, so I guess antibiotics are off the table? I sure hope you don’t die from a minor infection. Hope you never get diabetes or high blood pressure. No cough medicine or allergy medicine either, that’s annoying. I hope you don’t have any serious allergies, because EpiPens sure as shit count as “drugs”.

      • Dozzi92@lemmy.world
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        11 months ago

        To each their own for sure, but that right there is a combination for some very strange times. Sometimes fun is becoming part of the couch and traveling into outer space. They’re definitely not all get up and dance and have fun, though.

    • You999@sh.itjust.works
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      11 months ago

      To expand on the urinary issues ketamine causes, the problem is that ketamine will recrystallize inside your blatter and ketamine crystals can be pretty sharp.

    • chitak166@lemmy.world
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      11 months ago

      Ketamine is definitely up there with ‘hip’ drugs not worth trying.

      Along with MDMA and Xanax.

      I don’t really respect anyone who does these because they’re usually living a lifestyle that leads to nowhere.

      • prole@sh.itjust.works
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        11 months ago

        You’d be shocked by how many very successful and incredibly intelligent people have used drugs (including MDMA). Many still use them regularly. MDMA, in the right setting and in moderation, can (will) be a life-affirming and beautiful experience.

        This honestly sounds like something a child would say after having D.A.R.E. in elementary school.

          • pineapple_pizza@lemmy.dexlit.xyz
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            11 months ago

            I know people like this. Though I should probably define regularly as once every few weeks for k. Probably closer to like 2 to 4 times a year for MDMA. Obviously if you’re doing stuff every day then you won’t be productive in a job

          • prole@sh.itjust.works
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            10 months ago

            You literally just replied to one, my guy.

            And yes, I know plenty of people like that. And chances are, so do you. You just don’t know it.

            Edit; in case you’re young, I don’t want anyone to take this as evidence that “drugs are ok”, or “they lied to us about cannabis/MDMA, so that means they lied about heroin too.” No. This is why we’d be much better off if they were just honest from the beginning. Not all drugs are created equal, but also the classification system in the US (and most modern nations) is not necessarily based on potential harm.

            So to be clear, my comment is not necessarily true for all drugs, I am specifically referring to MDMA right now (which, before becoming illegal, was used by doctors to great effect as an aid in couples’ therapy).

      • smooth_tea@lemmy.world
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        11 months ago

        MDMA not worth it? It’s euphoria and love in a pill, not addictive, and quite safe when you do not abuse it. Millions of people use it and have been using it for about half a century and the vast majority of it restricts it to when they’re partying with few side effects. I think you misjudge its use a bit.

        Yes it can be acutely abused because you’re chasing the dragon on nights that you do use it, but that is also a result of its illegal nature and a lack of education.

        Of the chemical variants of drugs, I’d say it’s probably one of the few that is actually worth it, besides LSD.

        • Dozzi92@lemmy.world
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          11 months ago

          Yeah, I try to tell people that there’s value in MDMA beyond just a night out dancing. My favorite times have been on a couch with friends, getting deep into one another and kind of exploring your minds. I’ve had some incredibly important and memorable conversations with people that I was able to become very close with because MDMA let us drop the walls and talk about things, which is something I cannot do face to face with someone sober. And I’m not an introvert by any stretch, I have no problem being the center of a conversation, I have no problem listening to others, but opening up about personal issues was something MDMA let me do, and say things I never could put into words.

          I’ve also stood in front of a wall of speakers and had bright lights and bass music thrown at me, and that’s also fun.

      • Hadriscus@lemm.ee
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        11 months ago

        Hmmm, I don’t know the second one but mdma is great fun. Of course you have to be in a good state of mind before trying, but it’s a potent empathogen that has its uses.

        • EatATaco@lemm.ee
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          11 months ago

          One of the most fun nights of my life is when I went to visit a friend at his university, we took some and he immediately ended up with some girl and disappeared on me.

          So I decided that I would just wander his campus looking for parties. I took shots with frat boys, danced with some gays guy out dressed in drag, played chess with some guy on the quad (he would have destroyed me even if I was sober), found another friend and went and partied with her and her lesbian friends (“wait you’re a lesbian now?” “Maybe not sure”) and then made the biggest mistake of my life when I turned down joining them when I was making a hasty exit after I noticed one of the girls was eating the other out right next to me on the couch.

          • Hadriscus@lemm.ee
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            11 months ago

            wild 😁 Yea I get how you’d want a do over heheh

            My experience is very vanilla coming after yours, but we had some of that and spent the entire night in my last floor apartment just chatting and drinking looking at the sea. It was full moon too. At one point I must have thought it was around midnight, I peeked at the east-facing window in my room and a big ball of fire was burning on the horizon. Time really flew this night…

  • lingh0e@sh.itjust.works
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    11 months ago

    Ketamine’s effects on respiratory shit is serious.

    I almost stopped breathing during an assisted experience because I didn’t realize mixing K with benzos was dangerous.

    • intensely_human@lemm.ee
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      11 months ago

      It’s how Elijah McClain died too. Young kid stopped by police for matching the description. They shot him full of ketamine and he died of respiratory failure.

      • takingbacksunday@lemmy.world
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        11 months ago

        Can’t recall all the details, but the impression I got was his respiratory failure was caused by the officer choking him with a knee on his windpipe. EMTs did give a very high dose of ketamine at 5mg/kg body weight, whereas I usually use 0.5-1mg/kg body weight to put patients under surgical anesthesia.

    • sock@lemmy.world
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      11 months ago

      was it Ks resp effects or the combination with another downer that was serious

      and therefore not Ks fault and solely youre fault for not researching the chem

    • kernelle@0d.gs
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      11 months ago

      Perry had been undergoing ketamine infusion therapy prior to his death, reportedly for depression and anxiety. The toxicology report adds: “At the high levels of ketamine found in his postmortem blood specimens, the main lethal effects would be from both cardiovascular overstimulation and respiratory depression.”

      He was getting it as treatment, but technically yes

      • Thetimefarm@lemm.ee
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        11 months ago

        He was definately taking it recreationally too, a therapeudic dose wouldn’t even be close to enough to OD on. Long term ketamine use can have it’s own risks if the dose isn’t kept very low.