I recently moved Nextcloud and Gitea from Containers on a Debian VM to Alpine LXCs running Alpine’s packages. I’ve never had Nextcloud’s web interface so snappy and my resource usage for both is next to 0. If you’re running Proxmox I’d highly recommend trying out Alpine LXCs if they package your services.
As pointed out, the DNS issue was fixed, and the other point made about Python wheels has also been addressed; quite a good chunk of packages on PyPi have had a musl wheel added in the past 6 months or so, including numpy & scipy. I’m also not certain if the Go part is true; probably somewhere around half of the Go apps I’m running as a container are running or were built on an Alpine base.