I recently went to the grocery store and before I started scanning at the self-checkout, I realized someone else had scanned a box of “Men’s libido max” pills and apparently left as it required ID or something to buy, and I guess they didn’t want to look someone in the face and buy it.

So then I had to look someone in the face while they cleared it from the register, probably thinking that I was the one who had the change of heart.

I mean the downsides are basically cost, another stick/blood draw, potential for false positive and further anxiety/testing. No weigh-in on whether or not any individual should at any specific time, but even less-invasive screenings are not zero risk.

Excerpt from the US Preventative Task Force about prostate cancer screening:

“An elevated PSA level may be caused by prostate cancer but can also be caused by other conditions, including an enlarged prostate (benign prostatic hyperplasia) and inflammation of the prostate (prostatitis). Some men without prostate cancer may therefore have positive screening results (ie, “false-positive” results). Men with a positive PSA test result may undergo a transrectal ultrasound-guided core-needle biopsy of the prostate to diagnose prostate cancer.”

It was a Minute Physics video. Only 2 minutes, and a great watch.

Unpackerr is usually used for unzipping files downloaded automatically by Radar or Sonarr, but it can also be configured to point to any folder, like your downloads. It’s fairly easy to set up, especially if you’re just pointing it to a folder.

I recently jumped to mint, and I have to say I’m very happy with it. I struggled with like two things but the OS is popular enough that there are walkthroughs for nearly everything. And I was able to get Linux-based or browser-based software for everything I did on my windows computer

Seconded. A very chill and entertaining informational podcast that benefits greatly from its conversational style.

And episodes can be about nearly anything. Forgiveness, the Cannonball Run, the Loch Ness monster, the sun, beavers, the Equal Rights Act. They’re all great. I’ve been listening since 2012.

Alpha Pheonix is a great channel with some really good electricity videos recently.

Similarly, I started always reaching out of my car to touch the outside paint above the door when climbing out of the car to prevent a static shock from rubbing against the sheet and discharging when I close the door.

SSRIs and SNRIs aren’t necessarily alpha blockers (although some similar drugs like mirtazipine (Remeron) have some action there).

SSRIs get their name because they are selective serotonin reuptake inhibitors, meaning the prevent reuptake of serotonin at the neuron junction, and that increases action of serotonin in that junction. And that is what causes the anti-anxiety or anti-depressive effects. SNRIs do the same thing, but with both serotonin and norepinephrine.

Many drugs have effects at other receptors (like histamine) that may cause adverse effects like sleepiness.

Beta blockers block the action of adrenaline/epinephrine at beta-adrenergic receptors, primarily found on the heart (beta-1) or lungs (beta-2). Beta blockers are primarily used in heart failure, heart arrhythmias, hypertension, and performance anxiety.

Alpha blocker also block adrenaline, but primarily in the vascular system (alpha-1). Alpha blockers are often used for enlarged prostate, hypertension, and some uses related to anxiety or PTSD.

Certain alpha and beta blockers can get into the brain and may have effects in anxiety have other effects like fatigue or weight gain.

Beta blockers work on the adrenergic system, not the lymphatic system. The lymphatic system is used to transport immune cells as well as fluid that has absorbed into the intercellular space from the circulatory system.

But yeah, they essentially block the function of adrenaline/epinephrine on the heart primarily, slowing heart rate and potentially helping with anxiety through action in the central nervous system.