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More customization = Higher chance something breaks.
Admittedly, chances are it’s just something minor like your icons looking weird or transparency breaking, and it’s not like it happens very often. However I have had it happen while I’m trying to focus on something and it’s definitely an annoyance I could do without.
I like that I can customize on the off chance that I need to fuck with something. But defaults have been getting better and better so i’ve done it less and less.
You mentioned KDE as your preferred DE so I’d suggest the Fedora KDE spin. The Fedora team has been putting a lot of work into it lately and it’s supposedly going to be upgraded to equal footing with gnome in the next Fedora release.